Anti-PRKCDBP antibody (75-160) (STJ11102892)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PRKCDBP (75-160) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAVIN3 |
| Gene ID | 112464 |
| Uniprot ID | CAVN3_HUMAN |
| Immunogen Region | 75-160 |
| Immunogen Sequence | SNTLAQLLAKAERVSSHANA AQERAVRRAAQVQRLEANHG LLVARGKLHVLLFKEEGEVP ASAFQKAPEPLGPADQSELG PEQLEA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 75-160 of human PRKCDBP (NP_659477.2). |
Additional Info
| Tissue Specificity | Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Strongly expressed in mammary and epithelial cells. |
| Post Translational Modifications | In vitro, phosphorylated by PRKCD. |
| Function | Regulates the traffic and/or budding of caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. |
| Protein Name | Caveolae-Associated Protein 3Cavin-3Protein Kinase C Delta-Binding ProteinSerum Deprivation Response Factor-Related Gene Product That Binds To C-KinaseHsrbc |
| Database Links | |
| Cellular Localisation | CytoplasmMembraneCaveolaCytosolLocalizes In The Caveolae In A Caveolin-Dependent Manner |
| Alternative Antibody Names | Anti-Caveolae-Associated Protein 3 antibodyAnti-Cavin-3 antibodyAnti-Protein Kinase C Delta-Binding Protein antibodyAnti-Serum Deprivation Response Factor-Related Gene Product That Binds To C-Kinase antibodyAnti-Hsrbc antibodyAnti-CAVIN3 antibodyAnti-PRKCDBP antibodyAnti-SRBC antibody |
Information sourced from Uniprot.org