• Immunofluorescence analysis of Hep G2 cells using PRELID1 Rabbit polyclonal antibody (STJ11105572) at a dilution of 1:100 (40x lens). Secondary antibody:Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of PRELID1 in paraffin-embedded human colon carcinoma tissue using PRELID1 Rabbit polyclonal antibody (STJ11105572) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Immunohistochemistry analysis of PRELID1 in paraffin-embedded human tonsil tissue using PRELID1 Rabbit polyclonal antibody (STJ11105572) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.

Anti-PRELID1 antibody (174-219) (STJ11105572)

SKU:
STJ11105572

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Preli Domain-Containing Protein 1-Mitochondrial (174-219) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRELID1
Gene ID: 27166
Uniprot ID: PRLD1_HUMAN
Immunogen Region: 174-219
Immunogen: Recombinant Protein corresponding to a sequence within amino acids 174-219 of human PRELID1 (NP_037369.1).
Immunogen Sequence: PSKTLVETAKEAKEKAKETA LAATEKAKDLASKAATKKQQ QQQQFV
Tissue Specificity Highly expressed in fetal liver.less expressed in fetal brain, lung, and kidney. At the adult stage, expression is drastically reduced in the liver but highly expressed in the spleen, brain, lung, lymph nodes and peripheral blood leukocytes.
Function Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.
Protein Name Preli Domain-Containing Protein 1 - Mitochondrial
25 Kda Protein Of Relevant Evolutionary And Lymphoid Interest
Px19-Like Protein
Database Links Reactome: R-HSA-6803204
Cellular Localisation Mitochondrion
Mitochondrion Intermembrane Space
Alternative Antibody Names Anti-Preli Domain-Containing Protein 1 - Mitochondrial antibody
Anti-25 Kda Protein Of Relevant Evolutionary And Lymphoid Interest antibody
Anti-Px19-Like Protein antibody
Anti-PRELID1 antibody
Anti-PRELI antibody
Anti-CGI-106 antibody
Anti-SBBI12 antibody

Information sourced from Uniprot.org

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