Anti-Prealbumin antibody [11606] (STJ400304)

Name: Anti-Prealbumin antibody [11606] (STJ400304)
SKU: STJ400304
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenN/D

STJ400304

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Short Description	Mouse monoclonal antibody anti-Prealbumin is suitable for use in ELISA research applications.
Applications	ELISA
Host	Mouse
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	11606
Isotype	IgG1
Conjugation	Unconjugated
Concentration	5.0 mg/ml (+/-10 %)
Formulation	50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Storage Instruction	Unspecified, storage at 2–8 °C
Immunoreactivity	80–120 % compared to the reference sample in an FIA test
Association Rate Constant	Not Determined (N/D)

Gene Symbol	TTR
Gene ID	7276
Uniprot ID	TTHY_HUMAN
Immunogen	N/D
Specificity	Antibody recognizes human prealbumin

Tissue Specificity	Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.
Post Translational Modifications	Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYLD1 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway. Sulfonation of the reactive cysteine Cys-30 enhances the stability of the native conformation of TTR, avoiding misassembly of the protein leading to amyloid formation.
Function	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Protein Name	Transthyretin Attr Prealbumin Tbpa
Database Links	Reactome: R-HSA-2453864 Reactome: R-HSA-2453902 Reactome: R-HSA-3000171 Reactome: R-HSA-6798695 Reactome: R-HSA-975634 Reactome: R-HSA-977225
Cellular Localisation	Secreted Cytoplasm
Alternative Antibody Names	Anti-Transthyretin antibody Anti-Attr antibody Anti-Prealbumin antibody Anti-Tbpa antibody Anti-TTR antibody Anti-PALB antibody

Information sourced from Uniprot.org