Host: |
Mouse |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Peroxiredoxin-1 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Monoclonal |
Clone ID: |
8E7 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: |
WB 1:1000-3000IF 1:100-200IHC 1:50-300 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PRDX1 |
Gene ID: |
5052 |
Uniprot ID: |
PRDX1_HUMAN |
Specificity: |
The antibody detects endogenous Peroxiredoxin 1 protein. |
Immunogen: |
Recombinant Protein of Peroxiredoxin-1 |
Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |
Protein Name | Peroxiredoxin-1Natural Killer Cell-Enhancing Factor ANkef-AProliferation-Associated Gene ProteinPagThioredoxin Peroxidase 2Thioredoxin-Dependent Peroxide Reductase 2Thioredoxin-Dependent Peroxiredoxin 1 |
Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-5628897Reactome: R-HSA-8862803Reactome: R-HSA-9818027 |
Cellular Localisation | CytoplasmMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
Alternative Antibody Names | Anti-Peroxiredoxin-1 antibodyAnti-Natural Killer Cell-Enhancing Factor A antibodyAnti-Nkef-A antibodyAnti-Proliferation-Associated Gene Protein antibodyAnti-Pag antibodyAnti-Thioredoxin Peroxidase 2 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 2 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 1 antibodyAnti-PRDX1 antibodyAnti-PAGA antibodyAnti-PAGB antibodyAnti-TDPX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance