Anti-PRDM2 antibody (1-176) (STJ115123)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PRDM2 (1-176) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRDM2 |
| Gene ID | 7799 |
| Uniprot ID | PRDM2_HUMAN |
| Immunogen Region | 1-176 |
| Immunogen Sequence | MNQNTTEPVAATETLAEVPE HVLRGLPEEVRLFPSAVDKT RIGVWATKPILKGKKFGPFV GDKKKRSQVKNNVYMWEVYY PNLGWMCIDATDPEKGNWLR YVNWACSGEEQNLFPLEINR AIYYKTLKPIAPGEELLVWY NGEDNPEIAAAIEEERASAR SKRSSPKSRKGKKKSQ |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-176 of human PRDM2 (NP_036363.2). |
Additional Info
| Tissue Specificity | Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. |
| Function | S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. |
| Protein Name | Pr Domain Zinc Finger Protein 2Gata-3-Binding Protein G3bLysine N-Methyltransferase 8Mtb-ZfMte-Binding ProteinPr Domain-Containing Protein 2Retinoblastoma Protein-Interacting Zinc Finger ProteinZinc Finger Protein Riz |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 2 antibodyAnti-Gata-3-Binding Protein G3b antibodyAnti-Lysine N-Methyltransferase 8 antibodyAnti-Mtb-Zf antibodyAnti-Mte-Binding Protein antibodyAnti-Pr Domain-Containing Protein 2 antibodyAnti-Retinoblastoma Protein-Interacting Zinc Finger Protein antibodyAnti-Zinc Finger Protein Riz antibodyAnti-PRDM2 antibodyAnti-KMT8 antibodyAnti-RIZ antibody |
Information sourced from Uniprot.org