| Function | Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha IsoformPp2a Subunit B Isoform B55-AlphaB55Pp2a Subunit B Isoform Pr55-AlphaPp2a Subunit B Isoform R2-AlphaPp2a Subunit B Isoform Alpha |
| Database Links | Reactome: R-HSA-2995383Reactome: R-HSA-69231Reactome: R-HSA-69273Reactome: R-HSA-975957Reactome: R-HSA-9860927 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform antibodyAnti-Pp2a Subunit B Isoform B55-Alpha antibodyAnti-B55 antibodyAnti-Pp2a Subunit B Isoform Pr55-Alpha antibodyAnti-Pp2a Subunit B Isoform R2-Alpha antibodyAnti-Pp2a Subunit B Isoform Alpha antibodyAnti-PPP2R2A antibody |
Information sourced from Uniprot.org