| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein phosphatase 1 regulatory subunit 3B is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R3B |
| Gene ID: | 79660 |
| Uniprot ID: | PPR3B_HUMAN |
| Specificity: | This antibody detects endogenous levels of PPP1R3B at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human PPP1R3B |
| Function | Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3b Hepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit Gl Protein Phosphatase 1 Regulatory Subunit 4 Pp1 Subunit R4 Protein Phosphatase 1 Subunit Gl Ptg |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 3b antibody Anti-Hepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit Gl antibody Anti-Protein Phosphatase 1 Regulatory Subunit 4 antibody Anti-Pp1 Subunit R4 antibody Anti-Protein Phosphatase 1 Subunit Gl antibody Anti-Ptg antibody Anti-PPP1R3B antibody Anti-PPP1R4 antibody |
Information sourced from Uniprot.org