| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-RelA-associated inhibitor is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP1R13L |
| Gene ID: | 10848 |
| Uniprot ID: | IASPP_HUMAN |
| Specificity: | This antibody detects endogenous levels of iASPP at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human iASPP |
| Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Is involved in NF-kappa-B dependent negative regulation of inflammatory response. |
| Protein Name | Rela-Associated Inhibitor Inhibitor Of Aspp Protein Protein Iaspp Nfkb-Interacting Protein 1 Ppp1r13b-Like Protein |
| Database Links | Reactome: R-HSA-6804759 |
| Cellular Localisation | Cytoplasm Nucleus Predominantly Cytoplasmic But Also Nuclear |
| Alternative Antibody Names | Anti-Rela-Associated Inhibitor antibody Anti-Inhibitor Of Aspp Protein antibody Anti-Protein Iaspp antibody Anti-Nfkb-Interacting Protein 1 antibody Anti-Ppp1r13b-Like Protein antibody Anti-PPP1R13L antibody Anti-IASPP antibody Anti-NKIP1 antibody Anti-PPP1R13BL antibody Anti-RAI antibody |
Information sourced from Uniprot.org
