Anti-PPIE antibody (STJA0009641)

SKU:
STJA0009641

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Peptidyl-prolyl cis-trans isomerase E is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPIE
Gene ID: 10450
Uniprot ID: PPIE_HUMAN
Specificity: This antibody detects endogenous levels of Cyclophilin E at Human, Mouse
Immunogen: Synthesized peptide derived from human Cyclophilin E
Function Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity.this requires proline isomerase activity.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase E
Ppiase E
Cyclophilin E
Cyclophilin-33
Rotamase E
Database Links Reactome: R-HSA-6781823
Reactome: R-HSA-6781827
Reactome: R-HSA-6782135
Reactome: R-HSA-6782210
Reactome: R-HSA-6798695
Reactome: R-HSA-72163
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Peptidyl-Prolyl Cis-Trans Isomerase E antibody
Anti-Ppiase E antibody
Anti-Cyclophilin E antibody
Anti-Cyclophilin-33 antibody
Anti-Rotamase E antibody
Anti-PPIE antibody
Anti-CYP33 antibody

Information sourced from Uniprot.org

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