Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Peptidyl-prolyl cis-trans isomerase E is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPIE |
Gene ID: |
10450 |
Uniprot ID: |
PPIE_HUMAN |
Specificity: |
This antibody detects endogenous levels of Cyclophilin E at Human, Mouse |
Immunogen: |
Synthesized peptide derived from human Cyclophilin E |
Function | Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity.this requires proline isomerase activity. |
Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase EPpiase ECyclophilin ECyclophilin-33Rotamase E |
Database Links | Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6798695Reactome: R-HSA-72163 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase E antibodyAnti-Ppiase E antibodyAnti-Cyclophilin E antibodyAnti-Cyclophilin-33 antibodyAnti-Rotamase E antibodyAnti-PPIE antibodyAnti-CYP33 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance