• Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100
  • Western blot analysis of lysate from HeLa cells, using PPID Antibody.
  • Western blot analysis of HeLa cells using Cyclophilin D Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-PPID antibody (321-370 aa) (STJ96509)

SKU:
STJ96509

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Peptidyl-prolyl cis-trans isomerase D (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPID
Gene ID: 5481
Uniprot ID: PPID_HUMAN
Immunogen Region: 321-370 aa
Specificity: Cyclophilin D Polyclonal Antibody detects endogenous levels of Cyclophilin D protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human PPID at the amino acid range 321-370
Function PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer.the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. (Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase D
Ppiase D
40 Kda Peptidyl-Prolyl Cis-Trans Isomerase
Cyclophilin-40
Cyp-40
Cyclophilin-Related Protein
Rotamase D
Database Links Reactome: R-HSA-8939211
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Nucleoplasm
Alternative Antibody Names Anti-Peptidyl-Prolyl Cis-Trans Isomerase D antibody
Anti-Ppiase D antibody
Anti-40 Kda Peptidyl-Prolyl Cis-Trans Isomerase antibody
Anti-Cyclophilin-40 antibody
Anti-Cyp-40 antibody
Anti-Cyclophilin-Related Protein antibody
Anti-Rotamase D antibody
Anti-PPID antibody
Anti-CYP40 antibody
Anti-CYPD antibody

Information sourced from Uniprot.org

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