Anti-POMGNT1 antibody (171-221 aa) (STJ194780)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human PMGT1 at the amino acid range 171-221
General Information
| Short Description | Rabbit polyclonal anti-Protein O-linked-mannose beta-1, 2-N-acetylglucosaminyltransferase 1 (171-221 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POMGNT1 |
| Gene ID | 55624 |
| Uniprot ID | PMGT1_HUMAN |
| Immunogen | Synthesized peptide derived from the human PMGT1 at the amino acid range 171-221 |
| Immunogen Region | 171-221 aa |
| Specificity | This antibody detects endogenous levels of PMGT1 at Human/Mouse/Rat |
Additional Info
| Function | Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity. |
| Protein Name | Protein O-Linked-Mannose Beta-1 -2-N-Acetylglucosaminyltransferase 1Pomgnt1Udp-Glcnac -Alpha-D-Mannoside Beta-1 -2-N-Acetylglucosaminyltransferase I.2Gnt I.2 |
| Database Links | Reactome: R-HSA-5083628Reactome: R-HSA-5173105 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Linked-Mannose Beta-1 -2-N-Acetylglucosaminyltransferase 1 antibodyAnti-Pomgnt1 antibodyAnti-Udp-Glcnac -Alpha-D-Mannoside Beta-1 -2-N-Acetylglucosaminyltransferase I.2 antibodyAnti-Gnt I.2 antibodyAnti-POMGNT1 antibodyAnti-MGAT1.2 antibodyAnti-UNQ746 antibodyAnti-PRO1475 antibody |
Information sourced from Uniprot.org