• Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-POMGNT1 antibody (171-221 aa) (STJ194780)

SKU:
STJ194780

Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein O-linked-mannose beta-1, 2-N-acetylglucosaminyltransferase 1 (171-221 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: POMGNT1
Gene ID: 55624
Uniprot ID: PMGT1_HUMAN
Immunogen Region: 171-221 aa
Specificity: This antibody detects endogenous levels of PMGT1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human PMGT1 at the amino acid range 171-221
Function Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Protein Name Protein O-Linked-Mannose Beta-1 -2-N-Acetylglucosaminyltransferase 1
Pomgnt1
Udp-Glcnac -Alpha-D-Mannoside Beta-1 -2-N-Acetylglucosaminyltransferase I.2
Gnt I.2
Database Links Reactome: R-HSA-5083628
Reactome: R-HSA-5173105
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Protein O-Linked-Mannose Beta-1 -2-N-Acetylglucosaminyltransferase 1 antibody
Anti-Pomgnt1 antibody
Anti-Udp-Glcnac -Alpha-D-Mannoside Beta-1 -2-N-Acetylglucosaminyltransferase I.2 antibody
Anti-Gnt I.2 antibody
Anti-POMGNT1 antibody
Anti-MGAT1.2 antibody
Anti-UNQ746 antibody
Anti-PRO1475 antibody

Information sourced from Uniprot.org

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