Anti-POLDIP2 antibody (250-350) (STJ118257)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal POLDIP2 (250-350) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POLDIP2 |
| Gene ID | 26073 |
| Uniprot ID | PDIP2_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | MGMREAQNSHVYWWRYCIRL ENLDSDVVQLRERHWRIFSL SGTLETVRGRGVVGREPVLS KEQPAFQYSSHVSLQASSGH MWGTFRFERPDGSHFDVRIP P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human POLDIP2 (NP_056399.1). |
Additional Info
| Function | Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1). |
| Protein Name | Polymerase Delta-Interacting Protein 238 Kda Dna Polymerase Delta Interaction ProteinP38 |
| Database Links | |
| Cellular Localisation | Mitochondrion MatrixNucleusMainly Localizes To The Mitochondrial MatrixA Small Fraction Localizes In The Nucleus |
| Alternative Antibody Names | Anti-Polymerase Delta-Interacting Protein 2 antibodyAnti-38 Kda Dna Polymerase Delta Interaction Protein antibodyAnti-P38 antibodyAnti-POLDIP2 antibodyAnti-PDIP38 antibodyAnti-POLD4 antibodyAnti-HSPC017 antibody |
Information sourced from Uniprot.org