Anti-PLXND1 antibody (170-250 aa) (STJ192394)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 170-250
General Information
| Short Description | Rabbit polyclonal anti-Plexin-D1 (170-250 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLXND1 |
| Gene ID | 23129 |
| Uniprot ID | PLXD1_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 170-250 |
| Immunogen Region | 170-250 aa |
| Specificity | PLXD1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. |
| Protein Name | Plexin-D1 |
| Database Links | Reactome: R-HSA-416700Reactome: R-HSA-9013508Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCell ProjectionLamellipodium Membrane |
| Alternative Antibody Names | Anti-Plexin-D1 antibodyAnti-PLXND1 antibodyAnti-KIAA0620 antibody |
Information sourced from Uniprot.org