| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLS1 |
| Gene ID: | 5357 |
| Uniprot ID: | PLSI_HUMAN |
| Immunogen Region: | 1-110 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human PLS1 (NP_001165783.1). |
| Immunogen Sequence: | MENSTTTISREELEELQEAF NKIDIDNSGYVSDYELQDLF KEASLPLPGYKVREIVEKIL SVADSNKDGKISFEEFVSLM QELKSKDISKTFRKIINKRE GITAIGGTST |
| Tissue Specificity | In small intestine, colon, and kidney.relatively lower levels of expression are detected in the lung and stomach. |
| Post Translational Modifications | Phosphorylated. |
| Function | Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions. |
| Protein Name | Plastin-1Intestine-Specific PlastinI-Plastin |
| Database Links | Reactome: R-HSA-9662360Reactome: R-HSA-9662361 |
| Cellular Localisation | CytoplasmCell ProjectionStereocilium |
| Alternative Antibody Names | Anti-Plastin-1 antibodyAnti-Intestine-Specific Plastin antibodyAnti-I-Plastin antibodyAnti-PLS1 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89683/358174/STJ11100745_1__65395.1713122481.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXNDC9 knockout (KO) HeLa cells, using [KO Validated] TXNDC9 Rabbit polyclonal antibody (STJ11100745) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
