| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLOD2 (470-650) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLOD2 |
| Gene ID: |
5352 |
| Uniprot ID: |
PLOD2_HUMAN |
| Immunogen Region: |
470-650 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 470-650 of human PLOD2/LH2 (NP_891988.1). |
| Immunogen Sequence: |
KTLRSEMNERNYFVRDKLDP DMALCRNAREMTLQREKDSP TPETFQMLSPPKGVFMYISN RHEFGRLLSTANYNTSHYNN DLWQIFENPVDWKEKYINRD YSKIFTENIVEQPCPDVFWF PIFSEKACDELVEEMEHYGK WSGGKHHDSRISGGYENVPT DDIHMKQVDLENVWLHFIRE F |
| Tissue Specificity | Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Protein Name | Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2Lysyl Hydroxylase 2Lh2 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Rough Endoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal Side |
| Alternative Antibody Names | Anti-Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2 antibodyAnti-Lysyl Hydroxylase 2 antibodyAnti-Lh2 antibodyAnti-PLOD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
