| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLOD2 |
| Gene ID: | 5352 |
| Uniprot ID: | PLOD2_HUMAN |
| Immunogen Region: | 260-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-380 of human PLOD2/LH2 (NP_000926.2). |
| Immunogen Sequence: | ILLNYFGNYVPNSWTQDNGC TLCEFDTVDLSAVDVHPNVS IGVFIEQPTPFLPRFLDILL TLDYPKEALKLFIHNKEVYH EKDIKVFFDKAKHEIKTIKI VGPEENLSQAEARNMGMDFC R |
| Tissue Specificity | Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types. Isoform 2 is specifically expressed in skin, lung, dura and aorta. |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Protein Name | Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2Lysyl Hydroxylase 2Lh2 |
| Database Links | Reactome: R-HSA-1650814 |
| Cellular Localisation | Rough Endoplasmic Reticulum MembranePeripheral Membrane ProteinLumenal Side |
| Alternative Antibody Names | Anti-Procollagen-Lysine -2-Oxoglutarate 5-Dioxygenase 2 antibodyAnti-Lysyl Hydroxylase 2 antibodyAnti-Lh2 antibodyAnti-PLOD2 antibody |
Information sourced from Uniprot.org