| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLIN3 (135-434) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLIN3 |
| Gene ID: |
10226 |
| Uniprot ID: |
PLIN3_HUMAN |
| Immunogen Region: |
135-434 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 135-434 of human PLIN3 (NP_005808.3). |
| Immunogen Sequence: |
MVSSAKDTVATQLSEAVDAT RGAVQSGVDKTKSVVTGGVQ SVMGSRLGQMVLSGVDTVLG KSEEWADNHLPLTDAELARI ATSLDGFDVASVQQQRQEQS YFVRLGSLSERLRQHAYEHS LGKLRATKQRAQEALLQLSQ VLSLMETVKQGVDQKLVEGQ EKLHQMWLSWNQKQLQGPEK EPPKPEQVESRALTMFRDIA QQLQATCTSLGSSIQGLPTN VKDQVQQARRQVEDLQATF |
| Post Translational Modifications | Phosphorylation at Tyr-251 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. |
| Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. |
| Protein Name | Perilipin-347 Kda Mannose 6-Phosphate Receptor-Binding Protein47 Kda Mpr-Binding ProteinCargo Selection Protein Tip47Mannose-6-Phosphate Receptor-Binding Protein 1Placental Protein 17Pp17 |
| Database Links | Reactome: R-HSA-163560Reactome: R-HSA-6811440Reactome: R-HSA-9613354Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9706019 |
| Cellular Localisation | Lipid DropletEndosome MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmMembrane Associated On EndosomesDetected In The Envelope And The Core Of Lipid Bodies And In Lipid Sails |
| Alternative Antibody Names | Anti-Perilipin-3 antibodyAnti-47 Kda Mannose 6-Phosphate Receptor-Binding Protein antibodyAnti-47 Kda Mpr-Binding Protein antibodyAnti-Cargo Selection Protein Tip47 antibodyAnti-Mannose-6-Phosphate Receptor-Binding Protein 1 antibodyAnti-Placental Protein 17 antibodyAnti-Pp17 antibodyAnti-PLIN3 antibodyAnti-M6PRBP1 antibodyAnti-TIP47 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
