• Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of 3T3 cells using PLA1A Polyclonal Antibody

Anti-PLA1A antibody (381-430 aa) (STJ95148)

SKU:
STJ95148

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospholipase A1 member A (381-430 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLA1A
Gene ID: 51365
Uniprot ID: PLA1A_HUMAN
Immunogen Region: 381-430 aa
Specificity: PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PLA1A at the amino acid range 381-430
Function Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein. Isoform 2: Hydrolyzes lyso-PS but not PS.
Protein Name Phospholipase A1 Member A
Phosphatidylserine-Specific Phospholipase A1
Ps-Pla1
Database Links Reactome: R-HSA-1482801
Cellular Localisation Secreted
Alternative Antibody Names Anti-Phospholipase A1 Member A antibody
Anti-Phosphatidylserine-Specific Phospholipase A1 antibody
Anti-Ps-Pla1 antibody
Anti-PLA1A antibody
Anti-NMD antibody
Anti-PSPLA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance