| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Plakophilin-4 (185-234 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PKP4 |
| Gene ID: | 8502 |
| Uniprot ID: | PKP4_HUMAN |
| Immunogen Region: | 185-234 aa |
| Specificity: | Plakophilin 4 Polyclonal Antibody detects endogenous levels of Plakophilin 4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PKP4 at the amino acid range 185-234 |
| Function | Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. |
| Protein Name | Plakophilin-4 P0071 |
| Database Links | Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 Reactome: R-HSA-9696264 Reactome: R-HSA-9696270 Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell Junction Desmosome Cytoplasm Cytoskeleton Spindle Midbody Cell Membrane Peripheral Membrane Protein Associated With The Pericentrosomal Region In Interphase And With Spindle Poles During Mitosis In Anaphase During Chromosome Segregation Is Recruited To The Central Microtubule Bundle Focussed At The Spindle Midzone And Ultimately Localizes To The Midbody At Cytokinesis Constituent Of The Midbody Cytoskeletal Matrix Colocalized With Desmoplakin At Desmosomal Junctional Plaques In Cultured Epithelial Cells |
| Alternative Antibody Names | Anti-Plakophilin-4 antibody Anti-P0071 antibody Anti-PKP4 antibody |
Information sourced from Uniprot.org