• Western blot analysis of PKP4 Antibody. The lane on the right is blocked with the PKP4 peptide.
  • Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using PKP4 Antibody. The lane on the right is blocked with the PKP4 peptide.
  • Western blot analysis of mouse-heart lysis using Plakophilin 4 antibody. Antibody was diluted at 1:2000

Anti-PKP4 antibody (185-234 aa) (STJ95150)

SKU:
STJ95150

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Plakophilin-4 (185-234 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PKP4
Gene ID: 8502
Uniprot ID: PKP4_HUMAN
Immunogen Region: 185-234 aa
Specificity: Plakophilin 4 Polyclonal Antibody detects endogenous levels of Plakophilin 4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PKP4 at the amino acid range 185-234
Function Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.
Protein Name Plakophilin-4
P0071
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Reactome: R-HSA-9696273
Cellular Localisation Cell Junction
Desmosome
Cytoplasm
Cytoskeleton
Spindle
Midbody
Cell Membrane
Peripheral Membrane Protein
Associated With The Pericentrosomal Region In Interphase And With Spindle Poles During Mitosis
In Anaphase
During Chromosome Segregation
Is Recruited To The Central Microtubule Bundle
Focussed At The Spindle Midzone And Ultimately Localizes To The Midbody At Cytokinesis
Constituent Of The Midbody Cytoskeletal Matrix
Colocalized With Desmoplakin At Desmosomal Junctional Plaques In Cultured Epithelial Cells
Alternative Antibody Names Anti-Plakophilin-4 antibody
Anti-P0071 antibody
Anti-PKP4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance