Anti-PKP4 antibody (185-234 aa) (STJ95150)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PKP4 at the amino acid range 185-234
General Information
| Short Description | Rabbit polyclonal anti-Plakophilin-4 (185-234 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PKP4 |
| Gene ID | 8502 |
| Uniprot ID | PKP4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PKP4 at the amino acid range 185-234 |
| Immunogen Region | 185-234 aa |
| Specificity | Plakophilin 4 Polyclonal Antibody detects endogenous levels of Plakophilin 4 protein. |
Additional Info
| Function | Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. |
| Protein Name | Plakophilin-4P0071 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell JunctionDesmosomeCytoplasmCytoskeletonSpindleMidbodyCell MembranePeripheral Membrane ProteinAssociated With The Pericentrosomal Region In Interphase And With Spindle Poles During MitosisIn AnaphaseDuring Chromosome SegregationIs Recruited To The Central Microtubule BundleFocussed At The Spindle Midzone And Ultimately Localizes To The Midbody At CytokinesisConstituent Of The Midbody Cytoskeletal MatrixColocalized With Desmoplakin At Desmosomal Junctional Plaques In Cultured Epithelial Cells |
| Alternative Antibody Names | Anti-Plakophilin-4 antibodyAnti-P0071 antibodyAnti-PKP4 antibody |
Information sourced from Uniprot.org