Anti-PITPNB antibody [5D11] (STJA0032636)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenFull length human recombinant protein of human PITPNB produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-PITPNB for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5D11 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PITPNB |
| Gene ID | 23760 |
| Uniprot ID | PIPNB_HUMAN |
| Immunogen | Full length human recombinant protein of human PITPNB produced in E.coli. |
Additional Info
| Tissue Specificity | Widely expressed in various tissues including brain. |
| Post Translational Modifications | Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting. |
| Function | Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function. |
| Protein Name | Phosphatidylinositol Transfer Protein Beta IsoformPi-Tp-BetaPtdins Transfer Protein BetaPtdinstp Beta |
| Database Links | Reactome: R-HSA-1483196 |
| Cellular Localisation | Golgi ApparatusGolgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Phosphatidylinositol Transfer Protein Beta Isoform antibodyAnti-Pi-Tp-Beta antibodyAnti-Ptdins Transfer Protein Beta antibodyAnti-Ptdinstp Beta antibodyAnti-PITPNB antibody |
Information sourced from Uniprot.org