| Host: | Mouse |
| Applications: | WB/IHC-P |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-PITPNB for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 5D11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: | Affinity Purified |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | PITPNB |
| Gene ID: | 23760 |
| Uniprot ID: | PIPNB_HUMAN |
| Immunogen: | Full length human recombinant protein of human PITPNB produced in E.coli. |
| Tissue Specificity | Widely expressed in various tissues including brain. |
| Post Translational Modifications | Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting. |
| Function | Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function. |
| Protein Name | Phosphatidylinositol Transfer Protein Beta IsoformPi-Tp-BetaPtdins Transfer Protein BetaPtdinstp Beta |
| Database Links | Reactome: R-HSA-1483196 |
| Cellular Localisation | Golgi ApparatusGolgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Phosphatidylinositol Transfer Protein Beta Isoform antibodyAnti-Pi-Tp-Beta antibodyAnti-Ptdins Transfer Protein Beta antibodyAnti-Ptdinstp Beta antibodyAnti-PITPNB antibody |
Information sourced from Uniprot.org
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