Function | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane. |
Protein Name | Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain |
Database Links | Reactome: R-HSA-1483213 |
Cellular Localisation | Phosphatidylserine Decarboxylase Beta Chain: Mitochondrion Inner MembraneSingle-Pass Membrane ProteinIntermembrane SidePhosphatidylserine Decarboxylase Alpha Chain: Mitochondrion Inner MembranePeripheral Membrane ProteinCytoplasmAnchored To The Mitochondrial Inner Membrane Through Its Interaction With The Integral Membrane Beta ChainIsoform 1: Mitochondrion Inner MembraneIsoform 2: Mitochondrion Inner MembraneLipid DropletPredominantly Localizes To Lipid Droplets In Lipid-Replete ConditionsAnd To Mitochondria In Lipid-Deplete Conditions |
Alternative Antibody Names | Anti-Phosphatidylserine Decarboxylase Proenzyme - Mitochondrial Cleaved Into - Phosphatidylserine Decarboxylase Beta Chain - Phosphatidylserine Decarboxylase Alpha Chain antibodyAnti-PISD antibody |
Information sourced from Uniprot.org