Host: |
Goat |
Applications: |
Pep-ELISA/WB/IHC |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-Pirin (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-0.3-1.0 µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:128000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
PIR |
Gene ID: |
8544 |
Uniprot ID: |
PIR_HUMAN |
Immunogen Region: |
N-Term |
Accession Number: |
NP_003653.1 |
Specificity: |
Variants (NP_003653.1; NP_001018119.1) encode the same protein |
Immunogen Sequence: |
GSSKKVTLSVLSREC |
Function | Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). |
Protein Name | PirinProbable Quercetin 2 -3-Dioxygenase PirProbable Quercetinase |
Database Links | Reactome: R-HSA-8935690 |
Cellular Localisation | NucleusCytoplasmPredominantly Localized In Dot-Like Subnuclear StructuresCytoplasmic Localization Of Pir Seems To Positively Correlate With Melanoma Progression |
Alternative Antibody Names | Anti-Pirin antibodyAnti-Probable Quercetin 2 -3-Dioxygenase Pir antibodyAnti-Probable Quercetinase antibodyAnti-PIR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance