• STJ70575 (0. 3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-Pirin antibody (N-Term) (STJ70575)

SKU:
STJ70575-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Pirin (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1.0 µg/ml
IHC-5µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PIR
Gene ID: 8544
Uniprot ID: PIR_HUMAN
Immunogen Region: N-Term
Accession Number: NP_003653.1
Specificity: Variants (NP_003653.1; NP_001018119.1) encode the same protein
Immunogen Sequence: GSSKKVTLSVLSREC
Function Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).
Protein Name Pirin
Probable Quercetin 2 -3-Dioxygenase Pir
Probable Quercetinase
Database Links Reactome: R-HSA-8935690
Cellular Localisation Nucleus
Cytoplasm
Predominantly Localized In Dot-Like Subnuclear Structures
Cytoplasmic Localization Of Pir Seems To Positively Correlate With Melanoma Progression
Alternative Antibody Names Anti-Pirin antibody
Anti-Probable Quercetin 2 -3-Dioxygenase Pir antibody
Anti-Probable Quercetinase antibody
Anti-PIR antibody

Information sourced from Uniprot.org

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