Anti-PIMREG antibody (1-247) (STJ118662)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PIMREG (1-247) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PIMREG |
| Gene ID | 54478 |
| Uniprot ID | PIMRE_HUMAN |
| Immunogen Region | 1-247 |
| Immunogen Sequence | MASRWQNMGTSVRRRSLQHQ EQLEDSKELQPVVSHQETSV GALGSLCRQFQRRLPLRAVN LNLRAGPSWKRLETPEPGQQ GLQAAARSAKSALGAVSQRI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PIMREG (NP_001182157.1). |
Additional Info
| Tissue Specificity | Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines. |
| Post Translational Modifications | Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle. |
| Function | During mitosis, may play a role in the control of metaphase-to-anaphase transition. |
| Protein Name | Protein PimregCalm-Interactor Expressed In Thymus And SpleenPicalm-Interacting Mitotic RegulatorRegulator Of Chromosome Segregation Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusPartially Localizes To The Nucleolus |
| Alternative Antibody Names | Anti-Protein Pimreg antibodyAnti-Calm-Interactor Expressed In Thymus And Spleen antibodyAnti-Picalm-Interacting Mitotic Regulator antibodyAnti-Regulator Of Chromosome Segregation Protein 1 antibodyAnti-PIMREG antibodyAnti-CATS antibodyAnti-FAM64A antibodyAnti-RCS1 antibody |
Information sourced from Uniprot.org