| Short Description : | Rabbit polyclonal anti-Phospho-Zinc finger C3HC-type protein 1-Ser354 (320-369 aa) for use in WB, IF and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZC3HC1 |
| Gene ID: | 51530 |
| Uniprot ID: | ZC3C1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human NIPA around the phosphorylation site of Ser354 at the amino acid range 320-369 |
| Immunogen Region: | 320-369 aa |
| Specificity: | Phospho-NIPA (S354) Polyclonal Antibody detects endogenous levels of NIPA protein only when phosphorylated at S354. |
| Post Translational Modifications | Phosphorylated. May also be weakly phosphorylated on Tyr residues. |
| Function | Required for proper positioning of a substantial amount of TPR at the nuclear basket (NB) through interaction with TPR. |
| Protein Name | Zinc Finger C3hc-Type Protein 1Nuclear-Interacting Partner Of AlkHnipaNuclear-Interacting Partner Of Anaplastic Lymphoma Kinase |
| Database Links | Reactome: R-HSA-9725371 |
| Cellular Localisation | NucleusNucleus EnvelopeResident Of The Nuclear Basket (Nb)Occurs At The Nuclear Envelopes (Ne) Of All Tpr-Containing Cell TypesIncluding Proliferating And Non-DividingTerminally Differentiated Cells Of Different Morphogenetic Origin |
| Alternative Antibody Names | Anti-Zinc Finger C3hc-Type Protein 1 antibodyAnti-Nuclear-Interacting Partner Of Alk antibodyAnti-Hnipa antibodyAnti-Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase antibodyAnti-ZC3HC1 antibodyAnti-NIPA antibodyAnti-HSPC216 antibody |
Information sourced from Uniprot.org
