• Western blot analysis of lysates from COS7 cells treated with HU 2nM 24h, using NIPA (Phospho-Ser354) Antibody. The lane on the right is blocked with the phospho peptide.

Anti-Phospho-ZC3HC1-Ser354 antibody (320-369 aa) (STJ90545)

SKU:
STJ90545

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Zinc finger C3HC-type protein 1-Ser354 (320-369 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZC3HC1
Gene ID: 51530
Uniprot ID: ZC3C1_HUMAN
Immunogen Region: 320-369 aa
Specificity: Phospho-NIPA (S354) Polyclonal Antibody detects endogenous levels of NIPA protein only when phosphorylated at S354.
Immunogen: The antiserum was produced against synthesized peptide derived from the human NIPA around the phosphorylation site of Ser354 at the amino acid range 320-369
Post Translational Modifications Phosphorylated. May also be weakly phosphorylated on Tyr residues.
Function Required for proper positioning of a substantial amount of TPR at the nuclear basket (NB) through interaction with TPR.
Protein Name Zinc Finger C3hc-Type Protein 1
Nuclear-Interacting Partner Of Alk
Hnipa
Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase
Database Links Reactome: R-HSA-9725371
Cellular Localisation Nucleus
Nucleus Envelope
Resident Of The Nuclear Basket (Nb)
Occurs At The Nuclear Envelopes (Ne) Of All Tpr-Containing Cell Types
Including Proliferating And Non-Dividing
Terminally Differentiated Cells Of Different Morphogenetic Origin
Alternative Antibody Names Anti-Zinc Finger C3hc-Type Protein 1 antibody
Anti-Nuclear-Interacting Partner Of Alk antibody
Anti-Hnipa antibody
Anti-Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase antibody
Anti-ZC3HC1 antibody
Anti-NIPA antibody
Anti-HSPC216 antibody

Information sourced from Uniprot.org

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