| Tissue Specificity | Expressed in the inner and outer plexiform layers of the retina (at protein level). |
| Function | Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synaptic membranes. May play a role in determining the specificity of intracellular fusion reactions. |
| Protein Name | Syntaxin-Binding Protein 1Protein Unc-18 Homolog 1Unc18-1Protein Unc-18 Homolog AUnc-18a |
| Database Links | Reactome: R-MMU-181429Reactome: -MMU-181430Reactome: -MMU-210500Reactome: -MMU-212676Reactome: -MMU-264642Reactome: -MMU-888590 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 1 antibodyAnti-Protein Unc-18 Homolog 1 antibodyAnti-Unc18-1 antibodyAnti-Protein Unc-18 Homolog A antibodyAnti-Unc-18a antibodyAnti-Stxbp1 antibody |
Information sourced from Uniprot.org
