• Western blot analysis of lysates from HepG2 cells treated with Na3VO4 0.3mM 40', using PLCG2 (Phospho-Tyr753) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunohistochemical analysis of paraffin-embedded Human colon cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PLCG2 (Phospho-Tyr753) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of various cells using Phospho-PLC Gamma 2 (Y753) Polyclonal Antibody

Anti-Phospho-PLC Gamma (Y753) antibody (STJ90768)

SKU:
STJ90768

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal anti-Phospho-PLC Gamma (Y753) antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Specificity: Phospho-PLC gamma 2 (Y753) polyclonal antibody detects endogenous levels of PLC gamma 2 protein only when phosphorylated at Y753.
Uniprot ID: PLCG2_HUMAN
Gene ID: 5336
Gene Symbol: PLCG2
Immunogen: Synthesized peptide derived from human PLC gamma2 around the phosphorylation site of Y753.
Immunogen Region: 690-770 aa
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Protein Name 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-2
Phosphoinositide Phospholipase C-Gamma-2
Phospholipase C-Iv
Plc-Iv
Phospholipase C-Gamma-2
Plc-Gamma-2
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-166016
Reactome: R-HSA-1855204
Reactome: R-HSA-202433
Reactome: R-HSA-2029485
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-5607764
Reactome: R-HSA-5621480
Reactome: R-HSA-9027277
Reactome: R-HSA-9664323
Reactome: R-HSA-983695
Alternative Antibody Names Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-2 antibody
Anti-Phosphoinositide Phospholipase C-Gamma-2 antibody
Anti-Phospholipase C-Iv antibody
Anti-Plc-Iv antibody
Anti-Phospholipase C-Gamma-2 antibody
Anti-Plc-Gamma-2 antibody
Anti-PLCG2 antibody

Information sourced from Uniprot.org

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