• Western blot analysis of lysates from K562 cells treated with H2O2 100uM 30', using PDE4D (Phospho-Ser190/53) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using PDE4D (Phospho-Ser190/53) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-PDE4B/C/D-Ser133/119/190 antibody (156-205 aa) (STJ90828)

SKU:
STJ90828

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4B and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4C and cAMP-specific 3 NA, 5 cyclic phosphodiesterase 4D-Ser133/119/190 (156-205 aa) is suitable for use in W
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE4B
PDE4D
5142
5144
5143
PDE4B_HUMAN
PDE4D_HUMAN
PDE4C_HUMAN
Immunogen Region: 156-205 aa
Specificity: Phospho-PDE4B/C/D (S133/119/190) Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein only when phosphorylated at S133/119/190.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PDE4D around the phosphorylation site of Ser190/53 at the amino acid range 156-205
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Protein Name Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b
Dpde4
Pde32
Database Links Reactome: R-HSA-180024
Alternative Antibody Names Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b antibody
Anti-Dpde4 antibody
Anti-Pde32 antibody
Anti-PDE4B antibody
Anti-DPDE4 antibody

Information sourced from Uniprot.org

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