| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospho-Ribosomal protein S6 kinase beta-2-Ser423 (389-438 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RPS6KB2 |
| Gene ID: |
6199 |
| Uniprot ID: |
KS6B2_HUMAN |
| Immunogen Region: |
389-438 aa |
| Specificity: |
Phospho-p70 S6 kinase Beta (S423) Polyclonal Antibody detects endogenous levels of p70 S6 kinase Beta protein only when phosphorylated at S423. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human p70 S6 Kinase beta around the phosphorylation site of Ser423 at the amino acid range 389-438 |
| Function | Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. |
| Protein Name | Ribosomal Protein S6 Kinase Beta-2S6k-Beta-2S6k270 Kda Ribosomal Protein S6 Kinase 2P70s6k2P70-S6k 2S6 Kinase-Related KinaseSrkSerine/Threonine-Protein Kinase 14bP70 Ribosomal S6 Kinase BetaS6k-BetaP70 S6 Kinase BetaP70 S6k-BetaP70 S6kbP70-Beta |
| Database Links | Reactome: R-HSA-198693Reactome: R-HSA-5674400 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Beta-2 antibodyAnti-S6k-Beta-2 antibodyAnti-S6k2 antibodyAnti-70 Kda Ribosomal Protein S6 Kinase 2 antibodyAnti-P70s6k2 antibodyAnti-P70-S6k 2 antibodyAnti-S6 Kinase-Related Kinase antibodyAnti-Srk antibodyAnti-Serine/Threonine-Protein Kinase 14b antibodyAnti-P70 Ribosomal S6 Kinase Beta antibodyAnti-S6k-Beta antibodyAnti-P70 S6 Kinase Beta antibodyAnti-P70 S6k-Beta antibodyAnti-P70 S6kb antibodyAnti-P70-Beta antibodyAnti-RPS6KB2 antibodyAnti-STK14B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
