• Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-Phospho-LCP2-Tyr145 antibody (STJ196427)

SKU:
STJ196427

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Lymphocyte cytosolic protein 2-Tyr145 is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LCP2
Gene ID: 3937
Uniprot ID: LCP2_HUMAN
Specificity: This antibody detects endogenous levels of Human Mouse SLP-76 (phospho-Tyr145)
Immunogen: Synthesized phosho peptide around human SLP-76 (Tyr145)
Post Translational Modifications Phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2. SYK-dependent phosphorylation is required for recruitment of PI3K signaling components.
Function Involved in T-cell antigen receptor mediated signaling.
Protein Name Lymphocyte Cytosolic Protein 2
Sh2 Domain-Containing Leukocyte Protein Of 76 Kda
Slp-76 Tyrosine Phosphoprotein
Slp76
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-202433
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Lymphocyte Cytosolic Protein 2 antibody
Anti-Sh2 Domain-Containing Leukocyte Protein Of 76 Kda antibody
Anti-Slp-76 Tyrosine Phosphoprotein antibody
Anti-Slp76 antibody
Anti-LCP2 antibody

Information sourced from Uniprot.org

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