• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-Phospho-HCLS1-Tyr378 antibody (STJ90643)

SKU:
STJ90643

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Hematopoietic lineage cell-specific protein-Tyr378 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HCLS1
Gene ID: 3059
Uniprot ID: HCLS1_HUMAN
Specificity: Phospho-Lck BP-1 (Y378) Polyclonal Antibody detects endogenous levels of Lck BP-1 protein only when phosphorylated at Y378.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Lck BP-1 (phospho Tyr378)
Post Translational Modifications Phosphorylated by FES. Phosphorylated by LYN, FYN and FGR after cross-linking of surface IgM on B-cells. Phosphorylation by LYN, FYN and FGR requires prior phosphorylation by SYK or FES.
Function Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Protein Name Hematopoietic Lineage Cell-Specific Protein
Hematopoietic Cell-Specific Lyn Substrate 1
Lckbp1
P75
Cellular Localisation Membrane
Peripheral Membrane Protein
Cytoplasm
Mitochondrion
Alternative Antibody Names Anti-Hematopoietic Lineage Cell-Specific Protein antibody
Anti-Hematopoietic Cell-Specific Lyn Substrate 1 antibody
Anti-Lckbp1 antibody
Anti-P75 antibody
Anti-HCLS1 antibody
Anti-HS1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance