| Short Description : | Rabbit polyclonal anti-Phospho-HMG box-containing protein 1-Ser402 (371-420 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HBP1 |
| Gene ID: | 26959 |
| Uniprot ID: | HBP1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human HBP1 around the phosphorylation site of Ser402 at the amino acid range 371-420 |
| Immunogen Region: | 371-420 aa |
| Specificity: | Phospho-HBP1 (S402) Polyclonal Antibody detects endogenous levels of HBP1 protein only when phosphorylated at S402. |
| Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
| Protein Name | Hmg Box-Containing Protein 1Hmg Box Transcription Factor 1High Mobility Group Box Transcription Factor 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hmg Box-Containing Protein 1 antibodyAnti-Hmg Box Transcription Factor 1 antibodyAnti-High Mobility Group Box Transcription Factor 1 antibodyAnti-HBP1 antibody |
Information sourced from Uniprot.org
