Anti-Phospho-HBP1-Ser402 antibody (371-420 aa) (STJ90526)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human HBP1 around the phosphorylation site of Ser402 at the amino acid range 371-420
General Information
| Short Description | Rabbit polyclonal anti-Phospho-HMG box-containing protein 1-Ser402 (371-420 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HBP1 |
| Gene ID | 26959 |
| Uniprot ID | HBP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human HBP1 around the phosphorylation site of Ser402 at the amino acid range 371-420 |
| Immunogen Region | 371-420 aa |
| Specificity | Phospho-HBP1 (S402) Polyclonal Antibody detects endogenous levels of HBP1 protein only when phosphorylated at S402. |
Additional Info
| Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
| Protein Name | Hmg Box-Containing Protein 1Hmg Box Transcription Factor 1High Mobility Group Box Transcription Factor 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Hmg Box-Containing Protein 1 antibodyAnti-Hmg Box Transcription Factor 1 antibodyAnti-High Mobility Group Box Transcription Factor 1 antibodyAnti-HBP1 antibody |
Information sourced from Uniprot.org