Anti-Phospho-CXCR2-Ser347 antibody (311-360 aa) (STJ91096)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347 at the amino acid range 311-360
General Information
| Short Description | Rabbit polyclonal anti-Phospho-C-X-C chemokine receptor type 2-Ser347 (311-360 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CXCR2 |
| Gene ID | 3579 |
| Uniprot ID | CXCR2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human IL-8R beta/CDw128 beta around the phosphorylation site of Ser347 at the amino acid range 311-360 |
| Immunogen Region | 311-360 aa |
| Specificity | Phospho-IL-8R Beta (S347) Polyclonal Antibody detects endogenous levels of IL-8R Beta protein only when phosphorylated at S347. |
Additional Info
| Function | Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. |
| Protein Name | C-X-C Chemokine Receptor Type 2Cxc-R2Cxcr-2Cdw128bGro/Mgsa ReceptorHigh Affinity Interleukin-8 Receptor BIl-8r BIl-8 Receptor Type 2Cd Antigen Cd182 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 2 antibodyAnti-Cxc-R2 antibodyAnti-Cxcr-2 antibodyAnti-Cdw128b antibodyAnti-Gro/Mgsa Receptor antibodyAnti-High Affinity Interleukin-8 Receptor B antibodyAnti-Il-8r B antibodyAnti-Il-8 Receptor Type 2 antibodyAnti-Cd Antigen Cd182 antibodyAnti-CXCR2 antibodyAnti-IL8RB antibody |
Information sourced from Uniprot.org