Anti-Phospho-CDC25A-Ser178 antibody (144-193 aa) (STJ90929)

SKU:
STJ90929
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Phospho-M-phase inducer phosphatase 1-Ser178 (144-193 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CDC25A
Gene ID:993
Uniprot ID:MPIP1_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser178 at the amino acid range 144-193
Immunogen Region:144-193 aa
Specificity:Phospho-Cdc25A (S178) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S178.
Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin-E, in vitro.
Protein Name M-Phase Inducer Phosphatase 1
Dual Specificity Phosphatase Cdc25a
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-156711
Reactome: R-HSA-176187
Reactome: R-HSA-5689880
Reactome: R-HSA-69202
Reactome: R-HSA-69273
Reactome: R-HSA-69601
Reactome: R-HSA-69656
Reactome: R-HSA-8862803
Cellular Localisation
Alternative Antibody Names Anti-M-Phase Inducer Phosphatase 1 antibody
Anti-Dual Specificity Phosphatase Cdc25a antibody
Anti-CDC25A antibody

Information sourced from Uniprot.org