Western Blot analysis of 1 A549 cell 2 LPS 100ng/mL 30min treated, using primary antibody at 1:1000 dilution. Secondary antibody (STJS000791) was diluted at 1:10000

Anti-Phospho-CAPN2-Ser50 antibody (STJA0009846)

SKU:
STJA0009846
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Phospho-Calpain-2 catalytic subunit-Ser50 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAPN2
Gene ID: 824
Uniprot ID: CAN2_HUMAN
Specificity: This antibody detects endogenous levels of Human, Mouse, Rat Calpain 2 (Phospho Ser50)
Immunogen: Synthesized peptide derived from human Calpain 2 (Phospho Ser50)
Tissue Specificity Ubiquitous.
Function Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.
Protein Name Calpain-2 Catalytic Subunit
Calcium-Activated Neutral Proteinase 2
Canp 2
Calpain M-Type
Calpain Large Polypeptide L2
Calpain-2 Large Subunit
Millimolar-Calpain
M-Calpain
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-8862803
Cellular Localisation Cytoplasm
Cell Membrane
Translocates To The Plasma Membrane Upon Ca(2+) Binding
Alternative Antibody Names Anti-Calpain-2 Catalytic Subunit antibody
Anti-Calcium-Activated Neutral Proteinase 2 antibody
Anti-Canp 2 antibody
Anti-Calpain M-Type antibody
Anti-Calpain Large Polypeptide L2 antibody
Anti-Calpain-2 Large Subunit antibody
Anti-Millimolar-Calpain antibody
Anti-M-Calpain antibody
Anti-CAPN2 antibody
Anti-CANPL2 antibody

Information sourced from Uniprot.org

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