• Western blot analysis of lysates from NIH/3T3 cells, using CaMK2 alpha/beta/delta (Phospho-Thr305) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of 453 cells using Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody diluted at 1:1000
  • Immunohistochemistry analysis of paraffin-embedded human brain, using CaMK2 alpha/beta/delta (Phospho-Thr305) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of various cells using Phospho-CaMKII Alpha/Beta/Delta (T305) Polyclonal Antibody diluted at 1:1000

Anti-Phospho-CaMKI Alpha/beta/delta (T305) antibody (STJ90439)

SKU:
STJ90439

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal anti-Phospho-CaMKI Alpha/beta/delta (T305) antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Specificity: Phospho-CaMKII alpha/beta/delta (T305) polyclonal antibody detects endogenous levels of CaMKII alpha/beta/delta protein only when phosphorylated at T305.
Uniprot ID: KCC2A_HUMAN
Gene ID: 815
Gene Symbol: CAMK2A
Immunogen: Synthesized peptide derived from human CaMKIIalpha/beta/delta around the phosphorylation site of T305.
Immunogen Region: 240-320 aa
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission. Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity. Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity.
Protein Name Calcium/Calmodulin-Dependent Protein Kinase Type Ii Subunit Alpha
Cam Kinase Ii Subunit Alpha
Camk-Ii Subunit Alpha
Database Links Reactome: R-HSA-111932
Reactome: R-HSA-3371571
Reactome: R-HSA-399719
Reactome: R-HSA-4086398
Reactome: R-HSA-438066
Reactome: R-HSA-442982
Reactome: R-HSA-5576892
Reactome: R-HSA-5578775
Reactome: R-HSA-5673000
Reactome: R-HSA-5673001
Reactome: R-HSA-6802946
Reactome: R-HSA-6802952
Reactome: R-HSA-6802955
Reactome: R-HSA-877300
Reactome: R-HSA-9022692
Reactome: R-HSA-936837
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Cellular Localisation Cell Junction
Synapse
Postsynaptic Density
Cell Projection
Dendritic Spine
Dendrite
Postsynaptic Lipid Rafts
Alternative Antibody Names Anti-Calcium/Calmodulin-Dependent Protein Kinase Type Ii Subunit Alpha antibody
Anti-Cam Kinase Ii Subunit Alpha antibody
Anti-Camk-Ii Subunit Alpha antibody
Anti-CAMK2A antibody
Anti-CAMKA antibody
Anti-KIAA0968 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance