• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using CAD (Phospho-Thr456) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-CAD (T456) antibody (STJ91243)

SKU:
STJ91243

Current Stock:
Host: Rabbit
Applications: IHC-P, ELISA
Reactivity: Human, Mouse
Short Description: Rabbit polyclonal anti-Phospho-CAD (T456) antibody is suitable for use in Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
Specificity: Phospho-CAD (T456) polyclonal antibody detects endogenous levels of CAD protein only when phosphorylated at T456.
Uniprot ID: PYR1_HUMAN
Gene ID: 790
Gene Symbol: CAD
Immunogen: Synthesized peptide derived from human CAD around the phosphorylation site of T456.
Immunogen Region: 400-480 aa
Function This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Protein Name Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase
Database Links Reactome: R-HSA-500753
Cellular Localisation Cytoplasm
Nucleus
Cytosolic And Unphosphorylated In Resting Cells
Translocates To The Nucleus In Response To Egf Stimulation
Nuclear Import Promotes Optimal Cell Growth
Alternative Antibody Names Anti-Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase antibody
Anti-CAD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance