| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PHACTR1 (154-380) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PHACTR1 |
| Gene ID: |
221692 |
| Uniprot ID: |
PHAR1_HUMAN |
| Immunogen Region: |
154-380 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 154-380 of human PHACTR1 (NP_112210.1). |
| Immunogen Sequence: |
IKRGVLKEIYDKDGELSISN EEDSLENGQSLSSSQLSLPA LSEMEPVPMPRDPCSYEVLQ PSDIMDGPDPGAPVKLPCLP VKLSPPLPPKKVMICMPVGG PDLSLVSYTAQKSGQQGVAQ HHHTVLPSQIQHQLQYGSHG QHLPSTTGSLPMHPSGCRMI DELNKTLAMTMQRLESSEQR VPCSTSYHSSGLHSGDGVTK AGPMGLPEIRQVPTVVIECD DNKENVP |
| Tissue Specificity | Detected in umbilical vein endothelial cells. |
| Function | Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Involved in the regulation of cortical neuron migration and dendrite arborization. |
| Protein Name | Phosphatase And Actin Regulator 1 |
| Cellular Localisation | CytoplasmSynapseNucleusEnriched At SynapsesCytoplasmic In Resting CellsAnd Is Imported Into The Nucleus Upon Serum StimulationInteraction With Actin Prevents Nuclear Import |
| Alternative Antibody Names | Anti-Phosphatase And Actin Regulator 1 antibodyAnti-PHACTR1 antibodyAnti-KIAA1733 antibodyAnti-RPEL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
