Anti-PGF/PlGF/PLGF nanobody [SAA1244] (STJN000232)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000232
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-Placenta Growth Factor is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1244
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolPGF
Gene ID5228
Uniprot IDPLGF_HUMAN

Additional Info

Post Translational Modifications N-glycosylated.
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Protein Name Placenta Growth Factor
Plgf
Database Links Reactome: R-HSA-194313
Reactome: R-HSA-195399
Cellular Localisation Secreted
The Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin
Alternative Nanobody Names Anti-Placenta Growth Factor nanobody
Anti-Plgf nanobody
Anti-PGF nanobody
Anti-PGFL nanobody
Anti-PLGF nanobody

Information sourced from Uniprot.org

Citations

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