Anti-PGAM1 antibody [R06-5J4] (STJA0036996)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human PGAM1
General Information
| Short Description | Rabbit monoclonal anti-PGAM1 for use in WB and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5J4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PGAM1 |
| Gene ID | 5223 |
| Uniprot ID | PGAM1_HUMAN |
| Immunogen | A synthesized peptide derived from human PGAM1 |
Additional Info
| Tissue Specificity | Expressed in the liver and brain. Not found in the muscle. |
| Post Translational Modifications | Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. |
| Function | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate. Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate. |
| Protein Name | Phosphoglycerate Mutase 1Bpg-Dependent Pgam 1Phosphoglycerate Mutase Isozyme BPgam-B |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phosphoglycerate Mutase 1 antibodyAnti-Bpg-Dependent Pgam 1 antibodyAnti-Phosphoglycerate Mutase Isozyme B antibodyAnti-Pgam-B antibodyAnti-PGAM1 antibodyAnti-PGAMA antibodyAnti-CDABP0006 antibody |
Information sourced from Uniprot.org