• Western blot analysis of NIH-3T3 cells using PFK-B Polyclonal Antibody diluted at 1：1000
  • Western blot analysis of lysates from A549 and NIH/3T3 cells, using K6PL Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using PFK-B Polyclonal Antibody diluted at 1：1000

Anti-PFKL antibody (691-740 aa) (STJ95050)

SKU:
STJ95050

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATP-dependent 6-phosphofructokinase, liver type (691-740 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PFKL
Gene ID: 5211
Uniprot ID: PFKAL_HUMAN
Immunogen Region: 691-740 aa
Specificity: PFK-B Polyclonal Antibody detects endogenous levels of PFK-B protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human K6PL at the amino acid range 691-740
Function Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway.
Protein Name Atp-Dependent 6-Phosphofructokinase - Liver Type
Atp-Pfk
Pfk-L
6-Phosphofructokinase Type B
Phosphofructo-1-Kinase Isozyme B
Pfk-B
Phosphohexokinase
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-70171
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Atp-Dependent 6-Phosphofructokinase - Liver Type antibody
Anti-Atp-Pfk antibody
Anti-Pfk-L antibody
Anti-6-Phosphofructokinase Type B antibody
Anti-Phosphofructo-1-Kinase Isozyme B antibody
Anti-Pfk-B antibody
Anti-Phosphohexokinase antibody
Anti-PFKL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance