Anti-PFKFB3 antibody (400-500) [S8MR] (STJ11101968)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11101968
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General Information

Short DescriptionRabbit monoclonal PFKFB3 (400-500) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS8MR
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:100-1:500
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPFKFB3
Gene ID5209
Uniprot IDF263_HUMAN
Immunogen Region400-500
Immunogen SequenceLDKSAEEMPYLKCPLHTVLK LTPVAYGCRVESIYLNVESV CTHRERSEDAKKGPNPLMRR NSVTPLASPEPTKKPRINSF EEHVASTSAALPSCLPPEVP T
SpecificityA synthetic peptide corresponding to a sequence within amino acids 400-500 of human PFKFB3 (NP_004557.1).

Additional Info

Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylation by AMPK stimulates activity.
Function Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate.
Protein Name 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 3
6pf-2-K/Fru-2 -6-P2ase 3
Pfk/Fbpase 3
6pf-2-K/Fru-2 -6-P2ase Brain/Placenta-Type Isozyme
Renal Carcinoma Antigen Ny-Ren-56
Ipfk-2 Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase
Database Links Reactome: R-HSA-9634600
Cellular Localisation
Alternative Antibody Names Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 3 antibody
Anti-6pf-2-K/Fru-2 -6-P2ase 3 antibody
Anti-Pfk/Fbpase 3 antibody
Anti-6pf-2-K/Fru-2 -6-P2ase Brain/Placenta-Type Isozyme antibody
Anti-Renal Carcinoma Antigen Ny-Ren-56 antibody
Anti-Ipfk-2 Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibody
Anti-PFKFB3 antibody

Information sourced from Uniprot.org

Citations

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