| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PFAS |
| Gene ID: | 5198 |
| Uniprot ID: | PUR4_HUMAN |
| Immunogen Region: | 1-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PFAS (NP_036525.1). |
| Immunogen Sequence: | MSPVLHFYVRPSGHEGAAPG HTRRKLQGKLPELQGVETEL CYNVNWTAEALPSAEETKKL MWLFGCPLLLDDVARESWLL PGSNDLLLEVGPRLNFSTPT STNIVSVCRATGLGPVDRVE TTRRYRLSFAHPPSAEVEAI ALATLHDRMTEQHFPHPIQS FSPESMPEPLNGPINILGEG RLALEKANQELGLALDSWDL DFYTKRFQELQRNPSTVEAF DLAQSNSEHSRHWFFKGQL |
| Function | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. |
| Protein Name | Phosphoribosylformylglycinamidine SynthaseFgam SynthaseFgamsFormylglycinamide Ribonucleotide AmidotransferaseFgar AmidotransferaseFgar-AtFormylglycinamide Ribotide AmidotransferasePhosphoribosylformylglycineamide Amidotransferase |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Phosphoribosylformylglycinamidine Synthase antibodyAnti-Fgam Synthase antibodyAnti-Fgams antibodyAnti-Formylglycinamide Ribonucleotide Amidotransferase antibodyAnti-Fgar Amidotransferase antibodyAnti-Fgar-At antibodyAnti-Formylglycinamide Ribotide Amidotransferase antibodyAnti-Phosphoribosylformylglycineamide Amidotransferase antibodyAnti-PFAS antibodyAnti-KIAA0361 antibody |
Information sourced from Uniprot.org