Anti-Peroxiredoxin 5 (PRDX5) antibody [SRM14767] (STJ11109497)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Peroxiredoxin 5 (PRDX5) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14767 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:2000IHC-P, 1:200-1:2000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRDX5 |
| Gene ID | 25824 |
| Uniprot ID | PRDX5_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | S-palmitoylated. Palmitoylation occurs on the active site, inhibiting its reactivity.therefore PRDX5 palmitoylation status determines its antioxidant capacity. Isoform Mitochondrial: S-palmitoylated. Depalmitoylated by ABHD10. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. |
| Protein Name | Peroxiredoxin-5 - MitochondrialAlu Corepressor 1Antioxidant Enzyme B166Aoeb166Liver Tissue 2d-Page Spot 71bPlpPeroxiredoxin VPrx-VPeroxisomal Antioxidant EnzymeTpx Type ViThioredoxin Peroxidase Pmp20Thioredoxin-Dependent Peroxiredoxin 5 |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-5628897 P30044-2 |
| Cellular Localisation | Isoform Mitochondrial: MitochondrionIsoform Cytoplasmic+Peroxisomal: CytoplasmPeroxisome MatrixImported Into Peroxisomes Via Peroxisomal Targeting Signal 1 Receptor Pex5 |
| Alternative Antibody Names | Anti-Peroxiredoxin-5 - Mitochondrial antibodyAnti-Alu Corepressor 1 antibodyAnti-Antioxidant Enzyme B166 antibodyAnti-Aoeb166 antibodyAnti-Liver Tissue 2d-Page Spot 71b antibodyAnti-Plp antibodyAnti-Peroxiredoxin V antibodyAnti-Prx-V antibodyAnti-Peroxisomal Antioxidant Enzyme antibodyAnti-Tpx Type Vi antibodyAnti-Thioredoxin Peroxidase Pmp20 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 5 antibodyAnti-PRDX5 antibodyAnti-ACR1 antibodyAnti-SBBI10 antibody |
Information sourced from Uniprot.org