| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Peroxiredoxin 2/PRP is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM0428 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB (H, M) 1:500-1:1000 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
Prdx2 |
| Gene ID: |
21672 |
| Uniprot ID: |
PRDX2_MOUSE |
| Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse PRP |
| Post Translational Modifications | The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). |
| Protein Name | Peroxiredoxin-2Thiol-Specific Antioxidant ProteinTsaThioredoxin Peroxidase 1Thioredoxin-Dependent Peroxide Reductase 1Thioredoxin-Dependent Peroxiredoxin 2 |
| Database Links | Reactome: R-MMU-3299685Reactome: -MMU-5628897 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Peroxiredoxin-2 antibodyAnti-Thiol-Specific Antioxidant Protein antibodyAnti-Tsa antibodyAnti-Thioredoxin Peroxidase 1 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 1 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 2 antibodyAnti-Prdx2 antibodyAnti-Tdpx1 antibodyAnti-Tpx antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
