Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Inactive tyrosine-protein kinase PEAK1 (111-160 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PEAK1 |
Gene ID: | 79834 |
Uniprot ID: | PEAK1_HUMAN |
Immunogen Region: | 111-160 aa |
Specificity: | SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human SGK269 at the amino acid range 111-160 |
Function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. |
Protein Name | Inactive Tyrosine-Protein Kinase Peak1Pseudopodium-Enriched Atypical Kinase 1Sugen Kinase 269Tyrosine-Protein Kinase Sgk269 |
Database Links | Reactome: R-HSA-9013420Reactome: R-HSA-9013424 |
Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionColocalizes With F-Actin In Serum-Rich MediumActin Colocalization Is Reduced During Serum Starvation |
Alternative Antibody Names | Anti-Inactive Tyrosine-Protein Kinase Peak1 antibodyAnti-Pseudopodium-Enriched Atypical Kinase 1 antibodyAnti-Sugen Kinase 269 antibodyAnti-Tyrosine-Protein Kinase Sgk269 antibodyAnti-PEAK1 antibodyAnti-KIAA2002 antibody |
Information sourced from Uniprot.org