| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inactive tyrosine-protein kinase PEAK1 (111-160 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PEAK1 |
| Gene ID: |
79834 |
| Uniprot ID: |
PEAK1_HUMAN |
| Immunogen Region: |
111-160 aa |
| Specificity: |
SgK269 Polyclonal Antibody detects endogenous levels of SgK269 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human SGK269 at the amino acid range 111-160 |
| Function | Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. |
| Protein Name | Inactive Tyrosine-Protein Kinase Peak1Pseudopodium-Enriched Atypical Kinase 1Sugen Kinase 269Tyrosine-Protein Kinase Sgk269 |
| Database Links | Reactome: R-HSA-9013420Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionFocal AdhesionColocalizes With F-Actin In Serum-Rich MediumActin Colocalization Is Reduced During Serum Starvation |
| Alternative Antibody Names | Anti-Inactive Tyrosine-Protein Kinase Peak1 antibodyAnti-Pseudopodium-Enriched Atypical Kinase 1 antibodyAnti-Sugen Kinase 269 antibodyAnti-Tyrosine-Protein Kinase Sgk269 antibodyAnti-PEAK1 antibodyAnti-KIAA2002 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
