| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-PCYT1A (268-367) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S2MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PCYT1A |
| Gene ID: |
5130 |
| Uniprot ID: |
PCY1A_HUMAN |
| Immunogen Region: |
268-367 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 268-367 of human PCYT1A (P49585). |
| Immunogen Sequence: |
EEKSIDLIQKWEEKSREFIG SFLEMFGPEGALKHMLKEGK GRMLQAISPKQSPSSSPTRE RSPSPSFRWPFSGKTSPPCS PANLSRHKAAAYDISEDEED |
| Tissue Specificity | Brain, placenta, liver, fetal and adult lung. |
| Post Translational Modifications | The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation. Monoubiquitinated by the SCF(FBXL2) complex, leading to proteasomal degradation. |
| Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
| Protein Name | Choline-Phosphate Cytidylyltransferase ACct-AlphaCtp -Phosphocholine Cytidylyltransferase ACct ACt APhosphorylcholine Transferase A |
| Database Links | Reactome: R-HSA-1483191 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinEndoplasmic ReticulumNucleusIt Can Interconvert Between An Inactive Cytosolic Form And An Active Membrane-Bound Form |
| Alternative Antibody Names | Anti-Choline-Phosphate Cytidylyltransferase A antibodyAnti-Cct-Alpha antibodyAnti-Ctp -Phosphocholine Cytidylyltransferase A antibodyAnti-Cct A antibodyAnti-Ct A antibodyAnti-Phosphorylcholine Transferase A antibodyAnti-PCYT1A antibodyAnti-CTPCT antibodyAnti-PCYT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
