| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PBXIP1 |
| Gene ID: | 57326 |
| Uniprot ID: | PBIP1_HUMAN |
| Immunogen Region: | 1-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_065385.2). |
| Immunogen Sequence: | MASCPDSDNSWVLAGSESLP VETLGPASRMDPESERALQA PHSPSKTDGKELAGTMDGEG TLFQTESPQSGSILTEETEV KGTLEGDVCGVEPPGPGDTV VQGDLQETTVVTGLGPDTQD LEGQSPPQSLPSTPKAAWIR EEGRCSSSDDDTDVDMEGLR RRRGREAGPPQPMVPLAVEN QAGGEGAGGE |
| Tissue Specificity | Expressed in early hematopoietic precursors. |
| Function | Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. |
| Protein Name | Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1Hematopoietic Pbx-Interacting Protein |
| Cellular Localisation | CytoplasmCytoskeletonNucleusShuttles Between The Nucleus And The CytosolMainly Localized In The CytoplasmAssociated With MicrotubulesDetected In Small Amounts In The Nucleus |
| Alternative Antibody Names | Anti-Pre-B-Cell Leukemia Transcription Factor-Interacting Protein 1 antibodyAnti-Hematopoietic Pbx-Interacting Protein antibodyAnti-PBXIP1 antibodyAnti-HPIP antibody |
Information sourced from Uniprot.org